HOUSTON -- Houston Texans owner Robert McNair and his wife are giving $100 million to the Baylor College of Medicine, according to a newspaper report.

The gift equals the largest donation ever made to the school, the Houston Chronicle reported in Wednesday editions.

The funds, made through the Robert and Janice McNair Foundation, will fund research into breast cancer, pancreatic cancer, juvenile diabetes and the neurosciences.

"We're pleased to be able to do this," McNair, a Baylor trustee, said Tuesday. "I hope it has a significant impact on not just Baylor and researchers throughout the Texas Medical Center but people in Houston and everywhere who suffer from these diseases."

Baylor officials were scheduled to announce the gift Wednesday.

The donation comes about a year and a half after Baylor trustee and energy magnate Dan Duncan gave Baylor $100 million for its cancer center. The two gifts are the largest ever given to facilities in Houston's Texas Medical Center.

Copyright 2007 by The Associated Press